Effects of probiotics on symptoms of anxiety and depression in adults: A pilot study
LE3 .A278 2015
Master of Science
The effects of probiotics on mental and physical health symptoms were examined in adults using a double-blind, crossover design. Participants consumed a probiotic (Lactobacillus helveticus and Bifidobacterium longum) powder and a placebo powder, each for five weeks, separated by a two-week wash-out period. One third of participants were assigned to a wait-list control group during the first 5 weeks before beginning the intervention phases. The mental and physical health measures were completed at the beginning and end of each phase. Fifty-five participants completed the first intervention phase and 49 also completed the second. Participants significantly improved on a measure of overall mental health during the probiotic condition compared to the placebo condition; however, there were no other differences between probiotic and placebo conditions on the other measures. All groups (probiotic, placebo, and wait-list control) showed improvements on measures of anxiety, depression, and gastrointestinal symptoms across the study period regardless of condition.
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