Novel monolayer protected clusters as supports for catalysts
LE3 .A278 2003
Gossage, Robert A.
Master of Science
This thesis details the design and synthesis of functional nanoparticles based on the assembly of modified thioctic acid derivatives; the majority of which contain a 2-aryl-2-oxazoline fragment. The oxazoline molecules studied herein were prepared by the treatment of an arylcyanide or related precursor with an appropriate amino-alcohol in the presence of a Lewis acid catalyst. Molecules designed for attachment to Au surfaces to function as surface "linker" (oxazoline ligand-containing) and "spacer" (ligand-free) fragments were made by the coupling of amines or alcohols to thioctic acid chloride or 'via' coupling of thioctic acid itself with primary amines (DCC protocols) to yield the desired amides. Gold monolayer protected clusters (WC's) derivatised with the linker fragments were prepared 'via' the Schiffron reaction. The use of these synthetic MPC's as catalysts for the Ni/Al-mediated cyclotrimerization of 2-cyclohexene-1-one and trimethylsilyl-acetylene was examined.
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